Author

M. Omar-Hmeadi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

S. Barg· 4 shared A. Tengholm· 3 shared A. Gucek· 2 shared P.-E. Lund· 2 shared D. Balboa· 1 shared H. Ibrahim· 1 shared H. Montaser· 1 shared J. Kvist· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersCell Biology

S. Barg

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell functionality

H. Ibrahim, D. Balboa, J. Saarimäki-Vire, H. Montaser, O. Dyachok, P.-E. Lund, M. Omar-Hmeadi, J. Kvist, O. P. Dwivedi, V. Lithovius, T. Barsby, V. Chandra, S. Eurola, J. Ustinov, T. Tuomi, , T. Otonkoski

This study shows that RFX6 haploinsufficiency impairs beta cell function, leading to reduced insulin secretion and increased diabetes risk.

bioRxiv · Nov 15, 2023 · PreprintCell Biology

Local PI(4,5)P2 generation controls fusion pore expansion during exocytosis

M. Omar-Hmeadi, A. Gucek, S. Barg

The paper shows that local PI(4,5)P2 signaling controls fusion pore expansion during exocytosis by recruiting endocytic machinery and preventing peptide release.

bioRxiv · Jan 26, 2022 · PreprintCell Biology

Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes

M. Omar-Hmeadi, P.-E. Lund, N. Gandasi, A. Tengholm, S. Barg

This study shows that paracrine inhibition of α-cell glucagon exocytosis is impaired in human type-2 diabetes, leading to elevated glucagon levels.

bioRxiv · Oct 1, 2019Cell Biology

Fusion pore regulation by Epac2/cAMP controls cargo release during insulin exocytosis

A. Gucek, N. R. Gandasi, M. Omar-Hmeadi, M. Bakke, S. O. Doskeland, A. Tengholm, S. Barg

This study shows that Epac2/cAMP regulates fusion pore expansion in insulin exocytosis, affecting hormone and transmitter release balance.

bioRxiv · Aug 29, 2018Cell Biology