Hypoxia and TNF-alpha modulate extracellular vesicle release from human induced pluripotent stem cell-derived cardiomyocytes
M. Viola, M. P. Bebelman, R. G. C. Maas, F. J. Verweij, C. S. Seinen, S. C. A. de Jager, P. Vader, D. M. Pegtel, J. P. G. Sluijter
This study investigates how hypoxia and TNF-alpha affect extracellular vesicle release from hiPSC-CMs under stress conditions, identifying nSmase2 and mTOR signaling pathways involved.
bioRxiv · Feb 1, 2024Cell Biology