Author

M. P. Chakraborty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

R. Das· 2 shared D. Das· 1 shared K. Gangopadhyay· 1 shared P. K. Das· 1 shared P. Kaul· 1 shared P. Mondal· 1 shared S. Bhattacharyya· 1 shared S. Chowdhury· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

R. Das

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2 papers

Recent·Most cited

E41K Mutation Activates Brutons Tyrosine Kinase by Stabilizing an Inositol Hexakisphosphate Dependent Invisible Dimer

R. Das, S. Chowdhury, M. P. Chakraborty, S. Roy, K. Gangopadhyay

The paper investigates the E41K mutation in BTK, showing it stabilizes an IP6-dependent PH-TH dimer, activating BTK independently of PIP3 binding.

bioRxiv · Jan 22, 2024Biochemistry

Molecular basis of VEGFR1 autoinhibition at the plasma membrane

M. P. Chakraborty, D. Das, P. Mondal, P. Kaul, S. Bhattacharyya, P. K. Das, R. Das

This study identifies a mechanism by which VEGFR1 remains constitutively inactive through juxtamembrane inhibition and phosphatase activity, explaining its differential regulation compared to VEGFR2.

bioRxiv · Jun 8, 2023Biochemistry