M. Papadaki

Myofibril orientation as a metric for characterizing heart disease

This paper introduces a method to quantify myofibrillar orientation in cardiac muscle and shows it detects greater disorientation in diseased tissue compared to healthy controls.

Myofilament Glycation in Diabetes Reduces Contractility by Inhibiting Tropomyosin Movement, is Rescued by cMyBPC Domains

This study identifies myofilament glycation in diabetes as a cause of reduced cardiac contractility, showing that cMyBPC domains can rescue this dysfunction.