Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum.
A. Luscher, F. Fröhlich, C. Barisch, C. Littlewood, J. Metcalfe, F. Leuba, A. Palma, M. Pirruccello, G. Cesareni, M. Stagi, T. C. Walther, T. Soldati, P. De Camilli, L. E. Swan
This study identifies F&H peptide-containing proteins that interact with OCRL/Dd5P4 in Dictyostelium discoideum, revealing their role in endocytic membrane cycling and potential involvement in Lowe Syndrome phenotypes.
bioRxiv · Apr 24, 2019Cell Biology