Author

F. Fröhlich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:yeast· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:Drosophila· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Moeller· 2 shared B. M. Esch· 2 shared C. Körner· 2 shared D. Januliene· 2 shared J.-H. Schäfer· 2 shared S. Walter· 2 shared A. Luscher· 1 shared A. Palma· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

A. Moeller

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Author profile →

4 papers

Recent·Most cited

The structure of the Orm2-containing serine palmitoyltransferase complex reveals distinct inhibitory potentials of yeast Orm proteins.

C. Körner, J.-H. Schäfer, B. M. Esch, K. Parey, S. Walter, D. Teis, D. Januliene, O. Schmidt, A. Moeller, F. Fröhlich

The paper determines the cryo-EM structure of the SPT-Orm2 complex and shows Orm2 has higher inhibitory potential than Orm1, despite similar structures.

bioRxiv · Jan 30, 2024Biochemistry

Structure of the yeast ceramide synthase

J.-H. Schäfer, L. Clausmeyer, C. Körner, B. M. Esch, V. N. Wolf, S. Walter, D. Januliene, A. Moeller, F. Fröhlich

This study determines the structure of the yeast ceramide synthase complex using cryo-EM, revealing its active state and inhibition mechanism by fumonisin B1.

bioRxiv · Oct 24, 2023Biochemistry

Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum.

A. Luscher, F. Fröhlich, C. Barisch, C. Littlewood, J. Metcalfe, F. Leuba, A. Palma, M. Pirruccello, G. Cesareni, M. Stagi, T. C. Walther, T. Soldati, P. De Camilli, L. E. Swan

This study identifies F&H peptide-containing proteins that interact with OCRL/Dd5P4 in Dictyostelium discoideum, revealing their role in endocytic membrane cycling and potential involvement in Lowe Syndrome phenotypes.

bioRxiv · Apr 24, 2019Cell Biology

A Systematic Approach to Identify Recycling Endocytic Cargo Depending on the GARP Complex

F. Fröhlich, S. Eising, L. Thiele

The paper identifies GARP complex-dependent recycling cargo in yeast using auxin-induced degradation and vacuolar proteomics/lipidomics.

bioRxiv · Oct 19, 2018Cell Biology