Author

M. Pugniere

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:flow cytometry· 1 Organism:mouse· 1

Frequent Co-Authors

C. Henriquet· 3 shared C. Cheneau· 2 shared E. J. Kremer· 2 shared K. Eichholz· 2 shared O. Paris· 2 shared T. T. P. Tran· 2 shared A. I. Lamond· 1 shared A. Padilla· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersPlant Biology

C. Henriquet

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Comprehensive Analysis of Neutrophil Immunomodulatory Properties and FcR Dynamics in Health and HIV-1 Infection and Therapy

S. Marsile-Medun, M. Souchard, D. Abba Moussa, V. Lorin, H. Mouquet, E. Reynaud, R. Dibsy, E. TUAILLON, D. MURIAUX, G. Ngo, M. Pugniere, M. Naranjo-Gomez, M. Pelegrin

The paper examines neutrophil immunomodulatory properties and FcR dynamics in HIV-1 infection and therapy, finding altered cytokine production and FcR expression in PLWH.

bioRxiv · Feb 13, 2024Immunology

A tripartite complex HIV-1 Tat-cyclophilin A-capsid protein enables Tat encapsidation that is required for HIV-1 infectivity

M. Schatz, L. Marty, C. Ounadjela, P. B. V. Tong, I. Cardace, C. Mettling, P.-E. Milhiet, L. Costa, C. Godefroy, M. Pugniere, J.-F. Guichou, J.-M. Mesnard, M. Blaise, B. Beaumelle

This study identifies a Tat-CypA-CA tripartite complex that enables Tat encapsidation, which is essential for HIV-1 infectivity and viral production.

bioRxiv · Aug 7, 2022Microbiology

Adenovirus-α-defensin complexes induce NLRP3-associated maturation of human phagocytes via TLR4 engagement

K. Eichholz, H. T. Tran, C. Cheneau, T. T. P. Tran, O. Paris, M. Pugniere, E. J. Kremer

This study shows HNP-1 binds HAdV capsids, redirects them to TLR4, triggering NLRP3 inflammasome and IL-1β release in human phagocytes without membrane disruption.

bioRxiv · Oct 26, 2021Immunology

Design of a new effector recognition specificity in a plant NLR immune receptor by molecular engineering of its integrated decoy domain

S. Cesari, Y. Xi, N. Declerck, V. Chalvon-Poulier, L. Mammri, M. Pugniere, C. Henriquet, K. Deguillen, A. Padilla, T. Kroj

This study demonstrates that molecular engineering of the integrated decoy domain of an NLR can expand its effector recognition spectrum to a new effector.

bioRxiv · Apr 24, 2021 · PreprintPlant Biology

Lactoferrin retargets adenoviruses to TLR4 to induce an abortive NLRP3-associated pyroptotic response in human dendritic cells

C. Cheneau, K. Eichholz, T. H. Tran, T. T. P. Tran, O. Paris, C. Henriquet, M. Pugniere, E. J. Kremer

This study shows lactoferrin redirects adenoviruses to TLR4, triggering an abortive pyroptotic response in dendritic cells that releases pro-inflammatory cytokines.

bioRxiv · Jun 3, 2020Immunology

PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28gamma

B. Jonik-Nowak, T. Menneteau, D. Fesquet, V. Baldin, C. Bonne-Andrea, F. Mechali, B. Fabre, P. Boisguerin, S. De Rossi, C. Henriquet, M. Pugniere, M. Ducoux-Petit, O. Burlet-Schiltz, A. I. Lamond, P. Fort, , O. Coux

This paper identifies PIP30/FAM192A as a novel cofactor of PA28gamma, showing it binds to PA28gamma and modulates its interactions with the 20S proteasome and coilin.

bioRxiv · Mar 27, 2018Cell Biology