Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells
M. E. Polak, S. Sirvent, K. Clayton, J. D. Davies, A. F. Vallejo, Z. Wu, J. Woo, J. Riddell, P. S. Stumpf, M. Rose-Zerilli, J. West, M. Pujato, X. Chen, C. H. Woelk, B. D. MacArthur, , H. Singh
The paper identifies IRF4 as a key transcription factor driving antigen cross-presentation in human Langerhans cells, distinguishing them from conventional dendritic cells.
bioRxiv · Feb 5, 2019 · PreprintImmunology