B. D. MacArthur

Dual Dean entrainment with volume ratio modulation for efficient co-encapsulation: Extreme single-cell indexing

This paper introduces Pirouette-seq, a method for efficient single-cell co-encapsulation with improved throughput and signal-to-noise ratio.

Heterogeneity and 'memory in stem cell populations

The paper proposes that cellular memories explain heterogeneity in stem cell populations and how this relates to changes in stem cell numbers and regenerative potency over time.

Single cell RNA sequence analysis of human bone marrow samples reveals new targets for isolation of skeletal stem cells using DNA-coated gold nanoparticles

The paper uses single-cell RNA sequencing to identify new targets for isolating skeletal stem cells from human bone marrow using DNA-coated gold nanoparticles.

Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells

The paper identifies IRF4 as a key transcription factor driving antigen cross-presentation in human Langerhans cells, distinguishing them from conventional dendritic cells.

Cell division history determines hematopoietic stem cell potency

This study uses single-cell profiling and deep learning to show that hematopoietic stem cell self-renewal declines with age due to stochastic division patterns and prior division history.

Information Theory and Stem Cell Biology

This paper reviews how information theory concepts are applied to single-cell data to understand stem cell behavior and variability.