Author

C. H. Woelk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. H. White· 2 shared D. A. Gutierrez· 2 shared J. E. Norton· 2 shared A. F. Vallejo· 1 shared A. G. Therien· 1 shared A. L. Reens· 1 shared B. D. MacArthur· 1 shared B. D. Topcuoglu· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

C. H. White

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3 papers

Recent·Most cited

Novel neutrophil subsets associated with sepsis, vascular dysfunction and metabolic alterations identified using systems immunology

R. Martinelli, U. Parthasarathy, Y. Kuang, G. Thakur, J. D. Hogan, T. P. Wyche, J. E. Norton, J. R. Killough, T. R. Sana, C. Beakes, B. Shyong, R. N. Zhang, D. A. Gutierrez, M. Filbin, D. C. Christiani, , C. H. White

The paper identifies novel neutrophil subsets in sepsis patients using systems immunology and links them to cytokines, metabolites, and lipids, enabling a predictive model for patient classification.

bioRxiv · Feb 1, 2022 · PreprintImmunology

Vaccine Hyporesponse Induced By Individual Antibiotic Treatment In Mice And Non-Human Primates Is Diminished Upon Recovery Of The Gut Microbiome

G. Swaminathan, M. Citron, J. Xiao, J. E. Norton, A. L. Reens, B. D. Topcuoglu, J. M. Maritz, K.-J. Lee, D. Freed, T. M. Weber, C. H. White, M. Kadam, E. Spofford, E. Bryant-Hall, G. Salituro, , G. D. Hannigan

This study shows that antibiotic-induced gut microbiome disruption reduces vaccine response in mice and non-human primates, but recovery of microbiome diversity restores immune responses.

bioRxiv · Apr 2, 2021Immunology

Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells

M. E. Polak, S. Sirvent, K. Clayton, J. D. Davies, A. F. Vallejo, Z. Wu, J. Woo, J. Riddell, P. S. Stumpf, M. Rose-Zerilli, J. West, M. Pujato, X. Chen, C. H. Woelk, B. D. MacArthur, , H. Singh

The paper identifies IRF4 as a key transcription factor driving antigen cross-presentation in human Langerhans cells, distinguishing them from conventional dendritic cells.

bioRxiv · Feb 5, 2019 · PreprintImmunology