Author

S. Sirvent

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. E. Polak· 2 shared A. Appios· 1 shared A. F. Vallejo· 1 shared A. Vallejo· 1 shared B. D. MacArthur· 1 shared C. H. Woelk· 1 shared C. L. Bennett· 1 shared C. Major· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

M. E. Polak

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity

A. Appios, J. Davies, S. Sirvent, S. Henderson, S. Trzebanski, J. Schroth, M. L. Law, I. Boal Carvalho, H. Yuan-Hao Kan, S. Lovlekar, C. Major, A. Vallejo, N. J. Hall, M. Ardern-Jones, S. M. Henson, , C. L. Bennett

The paper investigates how monocyte differentiation in adult skin leads to Langerhans cell identity through intrinsic and extrinsic factors.

bioRxiv · Nov 13, 2023Immunology

Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells

M. E. Polak, S. Sirvent, K. Clayton, J. D. Davies, A. F. Vallejo, Z. Wu, J. Woo, J. Riddell, P. S. Stumpf, M. Rose-Zerilli, J. West, M. Pujato, X. Chen, C. H. Woelk, B. D. MacArthur, , H. Singh

The paper identifies IRF4 as a key transcription factor driving antigen cross-presentation in human Langerhans cells, distinguishing them from conventional dendritic cells.

bioRxiv · Feb 5, 2019 · PreprintImmunology