Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
X. Y. Poh, F. K. Loh, C. Bai, H. T. Chong, W. K. Teo, J. M. Hong, Q. H. Miow, P. M. Thong, B. Vilaysane, T. H. Hu, S. Chhabra, Y. Wang, S. C. Tiong, S. M. Fong, M. Kamihigashi, , C. W. M. Ong
The paper identifies elevated MMPs and NETs in CNS-TB patients and shows MMP inhibition improves survival in a mouse model.
bioRxiv · Oct 5, 2023 · PreprintPathology
A. F. Vallejo, K. Harvey, T. Wang, K. Wise, L. M. Butler, J. Polo, J. T. Plummer, A. Swarbrick, L. G. Martelotto
This paper introduces snPATHO-Seq, a method for high-quality single nucleus RNA sequencing from FFPE samples, showing improved sensitivity and accuracy compared to existing methods.
bioRxiv · Aug 23, 2022 · PreprintCancer Biology
M. Ahmed, J. S. Mackenzie, R. Krause, B. Truebody, L. B. Tezera, D. Garay-Baquero, A. F. Vallejo, K. Govender, J. Adamson, P. Elkington, A. J. C. Steyn, A. Leslie
This study shows Mycobacterium tuberculosis senses IFN-γ via MmpL10, increasing respiration and virulence, and enhances INH efficacy against persistent bacteria.
bioRxiv · Nov 12, 2021Microbiology
J. Harrington, L. B. Esteban, J. Butement, A. F. Vallejo, S. I. R. Lane, B. Sheth, M. S. A. Jongen, R. Parker, P. S. Stumpf, R. C. G. Smith, B. D. MacArthur, M. J. Rose-Zerilli, M. E. Polak, T. J. Underwood, J. West
This paper introduces Pirouette-seq, a method for efficient single-cell co-encapsulation with improved throughput and signal-to-noise ratio.
bioRxiv · Apr 8, 2021Cell Biology
P. Rettman, M. D. Blunt, B. Mbiribindi, R. Fulton, R. Schittenhelm, A. F. Vallejo, L. Bastidas-Legarda, M. E. Polak, R. Ayala, A. W. E. Purcell, A. Al-Shamkhani, C. Retiere, S. I. Khakoo
This study shows that activating NK cells via KIR2DS2 with a peptide:MHC vaccine generates anti-tumor responses and identifies XPO1 as a cancer-associated ligand for KIR2DS2.
bioRxiv · Apr 15, 2020 · PreprintImmunology
M. E. Polak, S. Sirvent, K. Clayton, J. D. Davies, A. F. Vallejo, Z. Wu, J. Woo, J. Riddell, P. S. Stumpf, M. Rose-Zerilli, J. West, M. Pujato, X. Chen, C. H. Woelk, B. D. MacArthur, , H. Singh
The paper identifies IRF4 as a key transcription factor driving antigen cross-presentation in human Langerhans cells, distinguishing them from conventional dendritic cells.
bioRxiv · Feb 5, 2019 · PreprintImmunology