M. Rajaei

Direct inference of the distribution of fitness effects of spontaneous mutations from recombinant inbred C. elegans mutation accumulation lines

This study infers the distribution of fitness effects of mutations in C. elegans using recombinant inbred lines, finding that positive effects are common but LD can skew results.

Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery

The paper maps 3D genome structures in cancer tissues to identify structural changes and potential biomarkers across cancer progression stages.

Mutability of mononucleotide repeats, not oxidative stress, explains the discrepancy between laboratory-accumulated mutations and the natural allele-frequency spectrum in C. elegans

The study shows that differences in mutation spectra between lab and natural C. elegans populations are due to mononucleotide repeat mutability, not oxidative stress.