L. M. Johnson

Direct inference of the distribution of fitness effects of spontaneous mutations from recombinant inbred C. elegans mutation accumulation lines

This study infers the distribution of fitness effects of mutations in C. elegans using recombinant inbred lines, finding that positive effects are common but LD can skew results.

Cumulative effects of mutation and selection on susceptibility to bacterial pathogens in Caenorhabditis elegans

The paper examines how mutations and selection affect pathogen susceptibility in C. elegans, finding mutations increase susceptibility and selection acts on it, but no fitness tradeoffs are observed.

Mutability of mononucleotide repeats, not oxidative stress, explains the discrepancy between laboratory-accumulated mutations and the natural allele-frequency spectrum in C. elegans

The study shows that differences in mutation spectra between lab and natural C. elegans populations are due to mononucleotide repeat mutability, not oxidative stress.

Sexual selection theory meets disease vector control: Testing harmonic convergence as a "good genes" signal in Aedes aegypti mosquitoes

This study tests if harmonic convergence in Ae. aegypti mosquitoes signals good genes by analyzing acoustic traits and heritability of fitness traits across generations.

Short-term heritable variation overwhelms two hundred generations of mutational variance for metabolic traits in Caenorhabditis elegans

The paper quantifies short-term heritable variation in metabolic traits of C. elegans and finds it comparable to mutational variance, suggesting epigenetic factors may significantly contribute to metabolic disease heritability.

The mutational decay of male and hermaphrodite competitive fitness in the androdioecious nematode C. elegans, in which males are naturally rare

The paper estimates mutational effects on male and hermaphrodite competitive fitness in C. elegans, finding males decay faster due to higher mutation rates and mating variability.