Diverse chemotypes drive biased signaling by cannabinoid receptors
T. Miljus, F. M. Heydenreich, T. Gazzi, A. Kimbara, M. Rogers-Evans, M. Nettekoven, E. Zirwes, A. Osterwald, A. C. Rufer, C. Ullmer, W. Guba, C. Le Gouill, J. Fingerle, M. Nazare, U. Grether, , D. B. Veprintsev
This study identifies chemotype-specific biased signaling in cannabinoid receptors by analyzing ligand-induced signaling cascades.
bioRxiv · Nov 9, 2020 · PreprintPharmacology & Toxicology