Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
M. S. Anandachar, S. Roy, S. Sinha, B. Agyekum, S.-R. Ibeawuchi, H. Gementera, A. Amamoto, G. D. Katkar, P. Ghosh
The paper identifies a conserved molecular interface between WxxxE-effector proteins from gut pathogens and the host protein ELMO1, showing how pathogens exploit the host's engulfment pathway.
bioRxiv · Apr 9, 2023Immunology
C. Tindle, G. Katkar, A. Fonseca, S. Taheri, J. Lee, P. Maity, I. Sayed, S.-R. Ibeawuchi, E. Vidales, R. Pranadinata, M. Fuller, D. Stec, M. S. Anandachar, K. Perry, H. Lee, , P. Ghosh
This paper creates a biobank of patient-derived organoids to identify molecular subtypes of Crohn's disease and test subtype-specific therapies.
bioRxiv · Mar 11, 2023Immunology
A. Sharma, S. Achi, S. R. Ibeawuchi, M. S. Anandachar, H. Gementera, U. Chaudhury, F. Usmani, K. Vega, I. Sayed, S. Das
This study shows that ELMO1 and NOD2 interact to control intestinal inflammation and bacterial clearance, with their dysfunction linked to Crohn's disease.
bioRxiv · Jul 9, 2022Microbiology
G. D. Katkar, M. S. Anandachar, S. Sinha, S.-R. Ibeawuchi, C. R. Espinoza, J. Coates, Y. S. Malhotra, M. Mullick, V. Castillo, D. T. Vo, D. Sahoo, P. Ghosh
This paper identifies GIV as a NOD2-interactor that enhances bacterial sensing and signaling in macrophages, revealing how loss of function in the NOD2 1007fs variant impairs protective immune responses.
bioRxiv · Apr 26, 2022 · PreprintImmunology
I. M. Sayed, S.-R. Ibeawuchi, D. Lie, M. S. Anandachar, R. Pranadinata, M. Raffatellu, S. Das
The paper investigates how WxxxE bacterial effectors interact with ELMO1 to regulate inflammation, showing that ELMO1 differentiates pathogenic from commensal bacteria and enhances inflammatory responses through these interactions.
bioRxiv · Jun 7, 2021Microbiology