Author

M. Raffatellu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. Petras· 2 shared H. Zhi· 2 shared R. Gerner· 2 shared S.-P. Nuccio· 2 shared A. Aron· 1 shared A. Perez-Lopez· 1 shared A. T. Aron· 1 shared B. Gilston· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

D. Petras

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of Th17 immunity

C.-H. Lin, C.-J. Wu, S. Cho, R. Patkar, L.-L. Lin, M.-C. Chen, E. Israelsson, J. Betts, M. Niedzielska, S. A. Patel, H. G. Duong, R. R. Gerner, C.-Y. Hsu, M. Catley, R. A. Maciewicz, , L.-F. Lu

This study identifies intestinal regulatory T cells producing IL-27 to specifically regulate Th17 immunity in the gut, revealing a novel mechanism for tissue-specific immune control.

bioRxiv · Feb 20, 2023Immunology

The interaction of enteric bacterial effectors with the host engulfment pathway control innate immune responses

I. M. Sayed, S.-R. Ibeawuchi, D. Lie, M. S. Anandachar, R. Pranadinata, M. Raffatellu, S. Das

The paper investigates how WxxxE bacterial effectors interact with ELMO1 to regulate inflammation, showing that ELMO1 differentiates pathogenic from commensal bacteria and enhances inflammatory responses through these interactions.

bioRxiv · Jun 7, 2021Microbiology

CCL28 modulates neutrophil responses during infection with mucosal pathogens

A. Perez-Lopez, S. Silva, M. Lee, N. Dillon, S. Brandt, R. Gerner, K. Melchior, G. T. Walker, V. Sosa-Hernandez, R. Cervantes-Diaz, S. Romero-Ramirez, J. Maravillas-Montero, S.-P. Nuccio, V. Nizet, M. Raffatellu

This study shows CCL28 enhances neutrophil responses in mucosal infections, improving pathogen clearance in some cases but worsening disease in others.

bioRxiv · Mar 19, 2021Immunology

Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut.

H. Zhi, J. Behnsen, A. Aron, V. Subramanian, J. Liu, R. Gerner, D. Petras, K. Green, S. Price, J. Camacho, H. Hillman, J. Tjokrosurjo, N. Montaldo, E. Hoover, S. Treacy-Abarca, , M. Raffatellu

This study shows that the probiotic E. coli Nissle 1917 uses yersiniabactin to acquire zinc in inflamed gut conditions, enhancing its colonization.

bioRxiv · Jul 20, 2020Microbiology

Native Electrospray-based Metabolomics Enables the Detection of Metal-binding Compounds

A. T. Aron, D. Petras, R. Schmid, J. M. Gauglitz, I. Buttel, L. Antelo, H. Zhi, C. C. Saak, K. P. Malarney, E. Thines, R. J. Dutton, M. Raffatellu, P. C. Dorrestein

The paper introduces a method to detect metal-binding compounds using native electrospray ionization mass spectrometry with metal infusion and molecular networking.

bioRxiv · Oct 30, 2019 · PreprintBiochemistry