Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV
Alexey Stukalov, Virginie Girault, Vincent Grass, Özge Karayel, Valter Bergant, Christian Urban, Darya A. Haas, Yiqi Huang, Lila Oubraham, Anqi Wang, M. Sabri Hamad, Antonio Piras, Fynn M. Hansen, Maria C. Tanzer, Igor Paron, , Andreas Pichlmair
Concurrent multi-omics of SARS-CoV-2 and SARS-CoV in A549 cells, integrated by network diffusion, maps shared and virus-specific host perturbations and nominates antiviral drug hotspots.
Nature · Apr 12, 2021Peer-reviewedSystems Biology✦ In-depth digest