Author

M. Sagar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:proteomics· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Y. Moreau· 3 shared A. Fan· 1 shared A. Gupta· 1 shared A. J. Olson· 1 shared A. Kumar· 1 shared A. Olson· 1 shared A. Thomas· 1 shared A. Young· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

Y. Moreau

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Heterotypic responses against nsp12/nsp13 from prior SARS-CoV-2 infection associates with lower subsequent endemic coronavirus incidence

D. J. Bean, J. Monroe, Y. M. Liang, E. Borberg, Y. Senussi, Z. Swank, S. Chalise, D. Walt, J. Weinberg, M. Sagar

The paper finds that prior SARS-CoV-2 infection, but not vaccination, reduces subsequent symptomatic endemic coronavirus incidence and is associated with stronger CD8+ T cell responses to non-structural proteins.

bioRxiv · Oct 23, 2023 · PreprintImmunology

Mycobacterium tuberculosis disease associates with higher HIV-1-specific antibody responses

B. Adeoye, L. Nakiyingi, Y. Moreau, E. Nankya, A. J. Olson, M. Zhang, K. R. Jacobson, A. Gupta, Y. Manabe, M. C. Hosseinipour, J. Kumwenda, M. Sagar

This study shows that Mycobacterium tuberculosis disease enhances HIV-1-specific antibody responses in people living with HIV, including broader and more potent neutralizing antibodies and increased antibody-dependent cellular cytotoxicity.

bioRxiv · Dec 2, 2022 · PreprintMicrobiology

Vertical HIV-1 transmission in the setting of maternal broad and potent antibody responses

J. Tu, A. Kumar, E. Giorgi, J. A. Eudailey, C. LaBranche, D. Martinez, G. G. Fouda, Y. Moreau, A. Thomas, D. Montefiori, F. Gao, M. Sagar, S. R. Permar

This study examines maternal broadly neutralizing antibody (bnAb) specificities in HIV-transmitting and non-transmitting mothers to determine if certain bnAb specificities drive infant transmitted/founder virus selection.

bioRxiv · Feb 3, 2022Immunology

SNAPflex: a paper-and-plastic device for instrument-free RNA and DNA extraction from whole blood

N. Kolluri, N. Albarran, A. Fan, A. Olson, M. Sagar, A. Young, J. Gomez-Marquez, C. M. Klapperich

SNAPflex is a low-cost, portable device for extracting RNA and DNA from whole blood without instruments, showing improved performance over traditional methods for HIV and Plasmodium.

bioRxiv · Mar 14, 2020Bioengineering

HIV-1 co-receptor usage and variable loop contact impacts V3 loop bnAb susceptibility

L. Registre, Y. Moreau, S. Toksoz Ataca, S. Pulukuri, T. J. Henrich, N. Lin, M. Sagar

The paper develops a sequence-based algorithm to predict HIV-1 receptor usage and bnAb susceptibility, showing that CXCR4-using strains are less susceptible to V3 loop bnAbs due to structural interactions.

bioRxiv · Mar 5, 2019Microbiology