Author

Y. Moreau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

M. Sagar· 3 shared A. Arany· 1 shared A. Bezier· 1 shared A. Carpenter· 1 shared A. Chateigner· 1 shared A. Gupta· 1 shared A. J. Olson· 1 shared A. Kumar· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersMicrobiology

M. Sagar

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mycobacterium tuberculosis disease associates with higher HIV-1-specific antibody responses

B. Adeoye, L. Nakiyingi, Y. Moreau, E. Nankya, A. J. Olson, M. Zhang, K. R. Jacobson, A. Gupta, Y. Manabe, M. C. Hosseinipour, J. Kumwenda, M. Sagar

This study shows that Mycobacterium tuberculosis disease enhances HIV-1-specific antibody responses in people living with HIV, including broader and more potent neutralizing antibodies and increased antibody-dependent cellular cytotoxicity.

bioRxiv · Dec 2, 2022 · PreprintMicrobiology

Vertical HIV-1 transmission in the setting of maternal broad and potent antibody responses

J. Tu, A. Kumar, E. Giorgi, J. A. Eudailey, C. LaBranche, D. Martinez, G. G. Fouda, Y. Moreau, A. Thomas, D. Montefiori, F. Gao, M. Sagar, S. R. Permar

This study examines maternal broadly neutralizing antibody (bnAb) specificities in HIV-transmitting and non-transmitting mothers to determine if certain bnAb specificities drive infant transmitted/founder virus selection.

bioRxiv · Feb 3, 2022Immunology

How to maintain a high virulence: evolution of a killer in hosts of various susceptibilities.

A. Chateigner, Y. Moreau, D. Jiolle, C. Pontleve, C. Labrousse, A. Bezier, E. Herniou

The paper studies how a baculovirus maintains high virulence across different host susceptibilities through experimental evolution and modeling.

bioRxiv · Jun 20, 2019 · PreprintEvolutionary Biology

HIV-1 co-receptor usage and variable loop contact impacts V3 loop bnAb susceptibility

L. Registre, Y. Moreau, S. Toksoz Ataca, S. Pulukuri, T. J. Henrich, N. Lin, M. Sagar

The paper develops a sequence-based algorithm to predict HIV-1 receptor usage and bnAb susceptibility, showing that CXCR4-using strains are less susceptible to V3 loop bnAbs due to structural interactions.

bioRxiv · Mar 5, 2019Microbiology

Repurposed High-Throughput Images Enable Biological Activity Prediction For Drug Discovery

J. Simm, G. Klambauer, A. Arany, M. Steijaert, J. K. Wegner, E. Gustin, V. Chupakhin, Y. T. Chong, J. Vialard, P. Buijnsters, I. Velter, A. Vapirev, S. Singh, A. Carpenter, R. Wuyts, , H. Ceulemans

The paper repurposes high-throughput imaging data from a glucocorticoid receptor assay to predict activity in unrelated drug discovery assays, significantly increasing hit rates and chemical diversity.

bioRxiv · Mar 30, 2017Pharmacology & Toxicology