M. Schwarzer

The Impact of Parabacteroides distasonis Colonization on Hosts' Microbiome, Metabolome, Immune Responses, and Diabetes Onset

This paper investigates how Parabacteroides distasonis colonization affects the microbiome, immune responses, and diabetes onset in NOD mice, finding it induces insulitis and activates specific T-cells without causing broad inflammation.

Epithelial antigen presentation controls commensal-specific intraepithelial T-cells in the gut

This study shows that MHCII on intestinal epithelial cells drives commensal-specific intraepithelial T-cells and regulates epithelial turnover.

Gut microbe Lactiplantiballus plantarum undergoes different evolutionary trajectories between insects and mammals

This study tracks the evolutionary trajectories of Lactiplantibacillus plantarum in Drosophila and mammalian hosts, finding diet-driven evolution in insects and host-intrinsic factors driving divergence in mammals.

A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF/SPF phenotypes

Germ-free mice exhibit mast cells with impaired functionality and gut homing and do not develop food allergy

This study shows that gut microbiota is essential for mast cell maturation and gut homing, which are necessary for developing food allergy symptoms in mice.

D-Alanine esterification of teichoic acids contributes to Lactobacillus plantarum mediated intestinal peptidase expression and Drosophila growth promotion upon chronic undernutrition

This study identifies the pbpX2-dlt operon in Lactobacillus plantarum as critical for D-alanine esterification of teichoic acids, which enhances intestinal peptidase expression and promotes Drosophila growth under chronic undernutrition.