Author

F. Leulier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 7 Physiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 11 Organism:Drosophila· 7 Research Focus:host-pathogen & immune response· 7 Research Focus:metabolism & bioenergetics· 4 Assay:metagenomics· 4 Organism:mouse· 4 Assay:proteomics· 4 Research Focus:development & morphogenesis· 3

Frequent Co-Authors

B. Gillet· 4 shared F. De Vadder· 4 shared H. Akherraz· 4 shared H. Gervais· 4 shared S. Hughes· 4 shared I. Rahioui· 3 shared J. Consuegra· 3 shared P. da Silva· 3 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

B. Gillet

Mutual co-authors in cluster

Author profile →

11 papers

Recent·Most cited

Protein restriction associated with high fat induces metabolic dysregulation without obesity in juvenile mice

A. Joly, J.-L. Thoumas, A. Lambert, E. Caillon, F. Leulier, F. De Vadder

This study shows that a Western diet with protein restriction in juvenile mice causes metabolic dysregulation without obesity, including hyperglycemia and fatty liver.

bioRxiv · Jul 22, 2024Physiology

Semaglutide interferes with postnatal development of juvenile mice with compromised growth

A. Joly, L. Rebiffe, Y. Dusabyinema, J. Dellinger, F. Leulier, F. De Vadder

This study examines the effects of semaglutide on growth and metabolism in juvenile mice, finding it lowers blood glucose in normally growing mice but worsens growth impairment in stunted juveniles.

bioRxiv · May 6, 2024Physiology

Suboptimal refeeding compensates stunting in a mouse model of juvenile malnutrition

J.-L. Thoumas, A. Cavaroc, D. Sery, F. Leulier, F. De Vadder

This study shows that suboptimal refeeding diets can restore body length but impair glucose metabolism in male mice with early-life malnutrition, while optimal refeeding fully restores growth in females.

bioRxiv · Mar 25, 2024Physiology

Structure-Function analysis of Lactiplantibacillus plantarum DltE reveals D-alanylated lipoteichoic acids as direct symbiotic cues supporting Drosophila juvenile growth

N. Nikolopoulos, R. C. Matos, S. Ravaud, P. Courtin, H. Akherraz, S. Palussiere, V. Gueguen-Chaignon, M. Salomon-Mallet, A. Guillot, Y. Guerardel, M.-P. Chapot-Chartier, C. Grangeasse, F. Leulier

The paper identifies D-Ala-LTAs as symbiotic cues that support Drosophila juvenile growth by promoting intestinal peptidase expression through the action of DltE.

bioRxiv · Sep 14, 2022Microbiology

Intestinal GCN2 controls Drosophila systemic growth in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNA operons

T. Grenier, J. Consuegra, M. Galvao Ferrarini, H. Akherraz, L. Bai, Y. Dusabyinema, I. Rahioui, P. da Silva, B. Gillet, S. Hughes, C. Ramos, R. Matos, F. Leulier

The paper shows that Lactiplantibacillus plantarum uses r/tRNA operons to communicate with Drosophila, activating GCN2 in enterocytes to promote systemic growth.

bioRxiv · Oct 31, 2021Microbiology

Metabolic cooperation among commensal bacteria supports Drosophila juvenile growth under nutritional stress

J. Consuegra, T. Grenier, H. Akherraz, I. Rahioui, H. Gervais, P. da Silva, F. Leulier

This study identifies a metabolic cooperation between two Drosophila gut bacteria that enhances host growth under nutritional stress by exchanging metabolites.

bioRxiv · May 27, 2020Microbiology

A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF/SPF phenotypes

M. Darnaud, F. De Vadder, P. Bogeat, L. Boucinha, A.-L. Bulteau, A. Bunescu, C. Couturier, A. Delgado, H. Dugua, C. Elie, A. Mathieu, T. Novotna, D. A. Ouattara, S. Planel, A. Saliou, , A. Tamellini

bioRxiv · Dec 30, 2019Microbiology

Commensal bacteria differentially shape the nutritional requirements of Drosophila during juvenile growth

J. Consuegra, T. Grenier, P. Baa-Puyoulet, I. Rahioui, H. Akherraz, H. Gervais, N. Parisot, P. da Silva, H. Charles, F. Calevro, F. Leulier

This study shows how two commensal bacteria affect the nutritional needs of Drosophila larvae by providing essential nutrients and compensating for host deficiencies.

bioRxiv · Aug 7, 2019Microbiology

Bacterial adaptation to diet is a key evolutionary force shaping Drosophila-Lactobacillus symbiosis

M. E. Martino, P. Joncour, R. Leenay, H. Gervais, M. Shah, S. Hughes, B. Gillet, C. Beisel, F. Leulier

This study shows that bacterial adaptation to diet, not the host, drives the evolution of beneficial symbiosis between Drosophila and Lactobacillus.

bioRxiv · Feb 2, 2018Evolutionary Biology

Stable association of a Drosophila-derived microbiota with its animal partner and the nutritional environment upon transfer between populations and generations

M. Tefit, B. Gillet, P. Joncour, S. Hughes, F. Leulier

The paper shows that a Drosophila-derived microbiota remains stable when transferred between populations and generations, emphasizing the role of the nutritional substrate in microbiota dynamics.

bioRxiv · Feb 24, 2017Microbiology

D-Alanine esterification of teichoic acids contributes to Lactobacillus plantarum mediated intestinal peptidase expression and Drosophila growth promotion upon chronic undernutrition

R. C. Matos, H. Gervais, P. Joncour, M. Schwarzer, B. Gillet, M. E. Martino, P. Courtin, S. Hughes, M.-P. Chapot-Chartier, F. Leulier

This study identifies the pbpX2-dlt operon in Lactobacillus plantarum as critical for D-alanine esterification of teichoic acids, which enhances intestinal peptidase expression and promotes Drosophila growth under chronic undernutrition.

bioRxiv · Jan 5, 2017Microbiology