Author

M. Seiffert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 6

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:flow cytometry· 3 Assay:proteomics· 3 Assay:scRNA-seq· 3

Frequent Co-Authors

S. Dietrich· 4 shared T. Roider· 4 shared J.-P. Mallm· 3 shared P.-M. Bruch· 3 shared C. Schifflers· 2 shared F. Czernilofsky· 2 shared G. Mechtersheimer· 2 shared K. Rippe· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersCancer Biology

S. Dietrich

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Author profile →

6 papers

Recent·Most cited

Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities

T. Roider, M. A. Baertsch, D. Fitzgerald, H. Voehringer, B. J. Brinkmann, F. Czernilofsky, M. Knoll, L. Llao-Cid, P.-M. Bruch, N. Liebers, C. M. Schuerch, V. Passerini, A. Brobeil, G. Mechtersheimer, C. Mueller-Tidow, , S. Dietrich

Nature Cell Biology · Mar 1, 2024Peer-reviewedCancer Biology

High-dimensional single-cell definition of CLL T cells identifies Galectin-9 as novel immunotherapy target

L. L. Cid, J. K. Leong, I. F. Botana, Y. Paul, M. Wierz, A. Floerchinger, S. Gonder, G. Pagano, M. Chazotte, K. Bestak, C. Schifflers, M. Iskar, T. Roider, F. Czernilofsky, P.-M. Bruch, , M. Seiffert

The paper defines CLL T cell subtypes and identifies Galectin-9 as a novel immunotherapy target through single-cell and multi-omics analyses.

bioRxiv · Dec 15, 2022 · PreprintCancer Biology

Multi-layered chromatin proteomics identifies cell vulnerabilities in DNA repair

G. Sigismondo, L. Arseni, N. Palacio-Escat, T. G. Hofmann, M. Seiffert, J. Krijgsveld

This study uses multi-layered chromatin proteomics to identify cell vulnerabilities in DNA repair by analyzing chromatin dynamics and repair protein interactions.

bioRxiv · Aug 5, 2021Cancer Biology

EOMES and IL-10 regulate anti-tumor activity of PD-1+ CD4+ T-cells in B-cell Non-Hodgkin lymphoma

P. M. Roessner, L. LLaó Cid, E. Lupar, T. Roider, M. Bordas, C. Schifflers, A.-C. Gaupel, F. Kilpert, M. Krötschel, S. J. Arnold, L. Sellner, S. Stilgenbauer, S. Dietrich, P. Lichter, A. Izcue, M. Seiffert

bioRxiv · Mar 9, 2020Cancer Biology

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL

J. A. Wierzbinska, R. Toth, N. Ishaque, K. Rippe, J.-P. Mallm, L. Klett, D. Mertens, T. Zenz, T. Hielscher, M. Seifert, R. Kueppers, Y. Assenov, P. Lutsik, S. Stilgenbauer, P. M. Roessner, , D. B. Lipka

This study introduces Methyl-COOM, a method to identify cell-of-origin and CLL-specific epigenetic aberrations by analyzing DNA methylation patterns.

bioRxiv · Feb 4, 2020Cancer Biology

Dissecting intratumor heterogeneity of nodal B cell lymphomas on the transcriptional, genetic, and drug response level

T. Roider, J. Seufert, A. Uvarovskii, F. Frauhammer, M. Bordas, N. Abedpour, M. Stolarczyk, J.-P. Mallm, S. Rabe, P.-M. Bruch, H. Balke-Want, M. Hundemer, K. Rippe, B. Goeppert, M. Seiffert, , S. Dietrich

This study examines intratumor heterogeneity in B cell lymphomas by analyzing transcriptional, genetic, and drug response profiles across malignant subclones and immune cells.

bioRxiv · Dec 11, 2019Cancer Biology