Author

M. Shein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. K. Schuetz· 1 shared A. Schuetz· 1 shared C. Goebel· 1 shared C. Huels· 1 shared E. Mejias-Perez· 1 shared E. Sakata· 1 shared K. Gaertner· 1 shared K. Leitl· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. K. Schuetz

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2 papers

Recent·Most cited

Unravelling ATP processing by the AAA+ protein p97 at the atomic level

M. Shein, M. Hitzenberger, T. Cheng, S. Rout, K. Leitl, Y. Sato, M. Zacharias, E. Sakata, A. Schuetz

This study uses cryo-EM, NMR, and MD simulations to reveal the atomic-level mechanism of ATP processing by p97, identifying a metastable ADP.Pi state and its role in coordinating subunit actions.

bioRxiv · Aug 26, 2023Biophysics

Micro RNAs are minor constituents of extracellular vesicles and are hardly delivered to target cells

M. Albanese, Y.-F. A. Chen, C. Huels, K. Gaertner, T. Tagawa, E. Mejias-Perez, O. T. Keppler, C. Goebel, R. Zeidler, M. Shein, A. K. Schuetz, W. Hammerschmidt

This study investigates whether extracellular vesicles (EVs) deliver microRNAs to target cells and found that miRNAs are not effectively delivered or functional.

bioRxiv · May 20, 2020Cell Biology