Author

M. Siragusa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

I. Fleming· 2 shared A. Brum· 1 shared A. Chadt· 1 shared A. Papapetropoulos· 1 shared A. Weigert· 1 shared C. Jung· 1 shared C. Quast· 1 shared D. A. Duse· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

I. Fleming

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Inhibition of proline-rich-tyrosine kinase 2 restores cardioprotection by remote ischemic preconditioning in type 2 diabetes mellitus

R. Erkens, D. A. Duse, A. Brum, A. Chadt, S. Becher, M. Siragusa, C. Quast, J. Muessig, M. Roden, M. Cortese-Krott, E. Lammert, I. Fleming, C. Jung, H. Al-Hasani, G. Heusch, M. Kelm

This study shows that inhibiting Pyk2 restores cardioprotection lost in diabetes through improved endothelial function and eNOS activity during remote ischemic preconditioning.

bioRxiv · Apr 25, 2023 · PreprintPhysiology

A novel role for cystathionine gamma lyase in the control of p53: impact on endothelial senescence and metabolic reprograming

J. Hu, M. S. Leisegang, M. Looso, G. Dumbovic, J. Wittig, M.-K. Drekolia, S. Guenther, D. John, M. Siragusa, S. Zukunft, J. Oo, I. Wittig, S. Hille, A. Weigert, S. Knapp, , S. I. Bibli

This paper identifies CSE-p53 interaction as a regulator of endothelial cell senescence and metabolic reprogramming in aging, showing that restoring this interaction can prevent senescence and promote vascular repair.

bioRxiv · Sep 5, 2022 · PreprintCell Biology