Author

M. Sperk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:proteomics· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1

Frequent Co-Authors

U. Neogi· 4 shared A. T. Ambikan· 3 shared F. Mikaeloff· 3 shared P. Nowak· 3 shared S. Svensson Akusjarvi· 3 shared A. Sonnerborg· 2 shared A. Vegvari· 2 shared R. Benfeitas· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

U. Neogi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Implications of central carbon metabolism in SARS-CoV-2 replication and disease severity

S. Krishnan, H. Nordqvist, A. T. Ambikan, S. Gupta, M. Sperk, S. Svensson-Akusjarvi, F. Mikaeloff, R. Benfeitas, E. Saccon, S. M. Ponnan, J. E. Rodriguez, N. Nikouyan, A. Odeh, G. Ahlen, M. Asghar, , U. Neogi

This study investigates how SARS-CoV-2 affects central carbon metabolism in host cells and links metabolic changes to disease severity.

bioRxiv · Feb 24, 2021Microbiology

Distinct lipid profile, low-level inflammation and increased antioxidant defense as a signature in HIV-1 elite control status

M. Sperk, F. Mikaeloff, S. Svensson Akusjarvi, S. M. Ponnan, P. Nowak, A. Sonnerborg, U. Neogi

This study identifies a distinct lipid profile, reduced inflammation, and increased antioxidant defense in HIV-1 elite controllers compared to viremic progressors and healthy controls.

bioRxiv · Jul 2, 2020Microbiology

Dysregulation in mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells

S. Appelberg, S. Gupta, A. T. Ambikan, F. Mikaeloff, A. Vegvari, S. Svensson Akusjarvi, R. Benfeitas, M. Sperk, M. Stahlberg, S. Krishnan, K. Singh, J. M. Penninger, A. Mirazimi, U. Neogi

The paper identifies dysregulation in mTOR/HIF-1 signaling in SARS-CoV-2 infected cells through proteo-transcriptomics analysis.

bioRxiv · Apr 30, 2020Microbiology

Systemic inflammation and risk of age-associated diseases in people living with HIV on long term suppressive antiretroviral therapy

H. Babu, A. T. Ambikan, E. E. Gabriel, S. Svensson Akusjarvi, A. N. Palaniapan, V. Sundaraj, N. R. Muppani, M. Sperk, N. Cheedarla, R. Sridhar, S. P. Tripathy, P. Nowak, L. E. Hanna, U. Neogi

This study evaluates systemic inflammation and age-associated disease risk in HIV-positive individuals on long-term ART, finding persistent inflammation and telomere shortening despite viral suppression.

bioRxiv · May 24, 2019 · PreprintImmunology

M. Sperk · henhao