M. Suzanne

Mechanical state of pre-tumoral epithelia dictates subsequent tumour aggressiveness

The paper shows that increased cell contractility in pre-tumoral tissues drives tumour aggressiveness through dysplasia and junction weakening.

An easy-to-use microfluidic mechano-chemostat for tissues and organisms reveals that confined growth is accompanied with increased macromolecular crowding

This paper introduces a microfluidic device that enables controlled mechanical and chemical environments for studying biological samples, showing that confined growth increases macromolecular crowding.

Super-resolved live-cell imaging using Random Illumination Microscopy

This paper introduces Random Illumination Microscopy (RIM), a super-resolution technique that achieves high-resolution, low-toxicity, and fast imaging for live-cell studies.

Curling of epithelial monolayers reveals coupling between active bending and tissue tension

The paper studies epithelial curling to assess the role of active bending and tissue tension in morphogenesis, finding that curling arises from myosin-driven active curvature and is regulated by in-plane and out-of-plane stresses.

Physical and functional cell-matrix uncoupling in a developing tissue under tension

The paper investigates how mechanical tension is distributed between cells and the extracellular matrix during tissue development in Drosophila.