Author

M. T. Scherzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. McMahon· 2 shared A. Dupuy· 1 shared A. G. Rust· 1 shared A. Grossman· 1 shared A. Liu· 1 shared A. Vaishnavi· 1 shared B. D. Smith· 1 shared C. G. Kinsey· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

M. McMahon

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2 papers

Recent·Most cited

Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer

M. McMahon, P. C. Ghazi, K. T. O'Toole, S. Srinivas Boggaram, M. T. Scherzer, M. R. Silvis, Y. Zhang, M. Bogdan, B. D. Smith, G. Lozano, D. L. Flynn, E. Snyder, C. G. Kinsey

This study shows that combining ULK1/2 inhibition with KRASG12C inhibitors reduces lung cancer growth in preclinical models.

bioRxiv · Feb 6, 2024Cancer Biology

"Transposon Mutagenesis Reveals RBMS3 as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis."

A. Vaishnavi, J. Juan, M. T. Scherzer, J. E. VanVeen, C. Stehn, C. S. Hackett, A. Dupuy, S. A. Chmura, L. van der Weyden, J. Y. Newberg, K. M. Mann, A. Liu, A. G. Rust, W. A. Weiss, D. Adams, , M. McMahon

This paper identifies RBMS3 as a tumor suppressor that cooperates with BRAFV600E to promote malignant lung cancer progression using transposon mutagenesis and CRISPR validation.

bioRxiv · Feb 28, 2022 · PreprintCancer Biology