Author

M. Trebicz-Geffen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Ankri· 4 shared L. Sarid· 3 shared J. Sun· 2 shared Y. Shaulov· 2 shared C. Shimokawa· 1 shared d. romero· 1 shared E. Zanditenas· 1 shared H. Hisaeda· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersMicrobiology

S. Ankri

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4 papers

Recent·Most cited

Digestive exophagy of Bacterial Biofilms by an Amoeba Predator is Mediated by Specific Biofilm Recognition

E. Zanditenas, M. Trebicz-Geffen, L. Dominguez-Garcia, d. romero, I. Kolodkin-Gal, S. Ankri

This study shows that E. histolytica degrades bacterial biofilms via digestive exophagy, involving cysteine proteases and stress response modulation.

bioRxiv · Sep 24, 2022 · PreprintMicrobiology

Queuine salvaging in the human parasite Entamoeba histolytica

L. Sarid, J. Sun, J. Chittrakanwong, M. Trebicz-Geffen, P. Dedon, S. Ankri

This study identifies EhDUF2419 as the enzyme enabling Entamoeba histolytica to salvage queuine from gut bacteria, which is essential for tRNA modification and oxidative stress resistance.

bioRxiv · Jun 21, 2022 · PreprintMicrobiology

Entamoeba histolytica adaption to auranofin: a phenotypic and multi-omics characterization

Y. Shaulov, L. SARID, M. Trebicz-Geffen, S. Ankri

This study characterizes the adaptation of Entamoeba histolytica to auranofin through phenotypic and multi-omics analyses, revealing changes in gene expression, redox status, and drug sensitivity.

bioRxiv · Jun 23, 2021Microbiology

Queuine is a nutritional regulator of Entamoeba histolytica response to oxidative stress and a virulence attenuator

S. Nagaraja, M. W. Cai, J. Sun, H. Varet, L. Sarid, Y. Shaulov, M. Trebicz-Geffen, M. Mazumdar, R. Legendre, J.-Y. Coppee, T. Begley, P. C. Dedon, S. Gourinath, N. Guillen, Y. Saito-Nakano, , S. Ankri

This study shows queuine, a gut bacterial product, enhances Entamoeba histolytica's oxidative stress resistance while reducing its virulence by modifying tRNAs and altering gene expression.

bioRxiv · Apr 30, 2020Microbiology