Author

M. Tsunoda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:CITE-seq· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

H. Aoki· 3 shared K. Matsushima· 3 shared S. Shichino· 3 shared S. Ueha· 3 shared H. Abe· 2 shared H. Shimizu· 2 shared A. Hara· 1 shared A. Ito· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

H. Aoki

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CD8+ T-cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by clonal replacement

H. Aoki, M. Kitabatake, H. Abe, P. Xu, M. Tsunoda, S. Shichino, A. Hara, N. Ouji-Sageshima, C. Motozono, T. Ito, K. Matsushima, S. Ueha

The paper tracks CD8+ T-cell clonotypes after three SARS-CoV-2 mRNA vaccinations and finds that clonotypes from earlier shots are replaced by new ones after subsequent boosters.

bioRxiv · Aug 27, 2022 · PreprintImmunology

Clonal spreading of tumor-infiltrating T cells underlies the robust antitumor immune responses

H. Aoki, M. Tsunoda, H. Ogiwara, H. Shimizu, H. Abe, T. Abe, S. Shichino, K. Matsushima, S. Ueha

This study shows that polyclonal expansion of tumor-reactive T cells, not oligoclonal expansion, correlates with antitumor effects in response to anti-PD-L1 and anti-CD4 treatments.

bioRxiv · Apr 19, 2022Immunology

Role of TLR4 signaling on Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice

I. Matsuo, N. Kawamura, Y. Ohnuki, K. Suita, M. Ishikawa, T. Matsubara, Y. Mototani, A. Ito, Y. Hayakawa, M. Nariyama, A. Morii, K. Kiyomoto, M. Tsunoda, K. Gomi, S. Okumura

This study investigates how Porphyromonas gingivalis LPS affects cardiac function in mice via TLR4 signaling, showing that TLR4 inhibition improves cardiac function.

bioRxiv · Oct 7, 2021Physiology

T cell receptor (TCR) repertoire analysis reveals a highly conserved TCR repertoire in a bilateral tumor mouse model

M. Tsunoda, H. Aoki, H. Shimizu, S. Shichino, K. Matsushima, S. Ueha

This study shows that the TCR repertoire is highly conserved between bilateral tumors in a mouse model, supporting its use for temporal analysis of antitumor T cell responses.

bioRxiv · May 13, 2021 · PreprintImmunology