M. Y. Chen

In a Canine Model of Septic Shock, Cardiomyopathy Occurs Independent of Catecholamine Surges and Cardiac Microvascular Ischemia

This study shows that cardiac dysfunction in septic shock occurs without high catecholamine levels or microvascular ischemia, and epinephrine infusions cause prolonged microvascular perfusion issues.

Cardiac Magnetic Resonance Studies in a Large Animal Model that Simulates the Cardiac Abnormalities of Human Septic Shock

This study uses cardiac magnetic resonance imaging in a canine sepsis model to show that ventricular wall edema and structural changes, not preload or afterload, explain differences in cardiac function and survival outcomes during sepsis.

Innate immunity can distinguish beneficial from pathogenic rhizosphere microbiota

The paper shows that plants can distinguish between beneficial and pathogenic Pseudomonas fluorescens strains through distinct immune responses.

Regional dynamics of fractal dimension of the left ventricular endocardium from cine computed tomography images

The paper quantifies regional left ventricular function using fractal dimension from 4DCT images, finding significant differences in systolic FD changes between normal and abnormal subjects.

Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop

This study shows that MALAT1 regulates chimeric mRNA export via an m6A-dependent mechanism, influencing myeloid progenitor cell differentiation in hematopoiesis.