Author

R. L. Danner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Z.-X. Yu· 3 shared C. Natanson· 2 shared C. Y. Demirkale· 2 shared H. G. Klein· 2 shared J. Feng· 2 shared J. M. Elinoff· 2 shared J. Sun· 2 shared J. Wang· 2 shared

Activity by Year

2024-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

Z.-X. Yu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In a Canine Model of Septic Shock, Cardiomyopathy Occurs Independent of Catecholamine Surges and Cardiac Microvascular Ischemia

V. J. Ford, W. N. Applefeld, J. Wang, J. Sun, S. B. Solomon, H. G. Klein, J. Feng, J. Lertora, P. TORABI-PARIZI, R. L. Danner, M. A. Solomon, M. Y. Chen, C. Natanson

This study shows that cardiac dysfunction in septic shock occurs without high catecholamine levels or microvascular ischemia, and epinephrine infusions cause prolonged microvascular perfusion issues.

bioRxiv · Feb 5, 2024Physiology

Cardiac Magnetic Resonance Studies in a Large Animal Model that Simulates the Cardiac Abnormalities of Human Septic Shock

V. J. Ford, W. N. Applefeld, J. Wang, J. Sun, S. B. Solomon, S. Sidenko, J. Feng, C. Sheffield, H. G. Klein, Z.-X. Yu, P. TORABI-PARIZI, R. L. Danner, V. Sachdev, M. A. Solomon, M. Y. Chen, C. Natanson

This study uses cardiac magnetic resonance imaging in a canine sepsis model to show that ventricular wall edema and structural changes, not preload or afterload, explain differences in cardiac function and survival outcomes during sepsis.

bioRxiv · Feb 5, 2024Physiology

Endothelial PHD2 deficiency induces apoptosis resistance and inflammation via AKT activation and AIP1 loss independent of HIF2α

S. Wang, K. S. Awad, L.-Y. Chen, M. A. H. Siddique, G. A. Ferreyra, C. L. Wang, T. Joseph, Z.-X. Yu, K. Takeda, C. Y. Demirkale, Y. Zhao, J. M. Elinoff, R. L. Danner

bioRxiv · Feb 1, 2024Cell Biology

Disruption of DLL4/NOTCH1 Causes Dysregulated PPARγ/AKT Signaling in Pulmonary Arterial Hypertension

K. S. Awad, S. Wang, E. J. Dougherty, A. Keshavarz, C. Y. Demirkale, Z.-X. Yu, L. Miller, J. M. Elinoff, R. L. Danner

This study shows that DLL4/NOTCH1 signaling regulates PPARγ/AKT pathways in PAH, with potential therapeutic implications for vascular remodeling.

bioRxiv · Jan 31, 2024Cell Biology