R. Ho

Structure, function and assembly of soybean primary cell wall cellulose synthases

This study characterizes the structure and function of soybean primary cell wall cellulose synthases, revealing their assembly and interaction mechanisms for cellulose biosynthesis.

Molecular insights into phosphoethanolamine cellulose formation and secretion

This study elucidates the molecular mechanism of phosphoethanolamine (pEtN) modification and secretion of cellulose in Enterobacteriaceae, identifying key protein interactions and enzymatic roles.

Cognate Antigen Engagement Induces HIV-1 Expression In CD4+ T Cells From People On Long-Term ART

The paper shows that cognate antigen engagement in CD4+ T cells on long-term ART increases HIV-1 transcription through T cell activation, suggesting a role in viral rebound.

Multivalent DNA-encoded lectins on phage enable detecting compositional glycocalyx differences

This paper develops a phage-based liquid lectin array to detect subtle glycocalyx differences by displaying multivalent lectins on DNA-barcoded M13 phage.

Insights into substrate coordination and glycosyl transfer of poplar cellulose synthase-8

This study presents cryo-EM structures of poplar cellulose synthase-8 with substrates and products, revealing substrate coordination and catalytic mechanisms.

The Cell Adhesion Molecule TMIGD1 Binds to Moesin and Regulates Tubulin Acetylation and Cell Migration

This study identifies TMIGD1 as a tumor suppressor that binds moesin and regulates tubulin acetylation and cell migration through interactions with ERM family proteins.

Lineage Recording Reveals the Phylodynamics, Plasticity and Paths of Tumor Evolution

The paper tracks tumor evolution in a mouse model using lineage tracing and single-cell RNA-seq, revealing plasticity, fitness-associated programs, and stereotypical evolutionary trajectories.

TMIGD1, a putative tumor suppressor, induces G2-M cell cycle checkpoint arrest in colon cancer cells

This study identifies TMIGD1 as a tumor suppressor that arrests the cell cycle in colon cancer cells and is downregulated in human CRC, correlating with poor survival.

Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to energy sensing and autophagy

This study shows IGPR-1 activates AMPK, linking cell adhesion to autophagy through phosphorylation of ULK1 and Beclin-1, and identifies IKKβ as a key kinase in this pathway.

Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells

This study identifies parthenolide's covalent targeting of FAK1 in breast cancer cells, showing inhibition of FAK1-dependent pathways and cancer cell proliferation.

Adipose fin development and its relation to the evolutionary origins of median fins

The paper investigates adipose fin development in Corydoras aeneus to explore how the median fin fold contributes to the evolution of new median fins in vertebrates.