Immune tolerance of human induced pluripotent stem cell-derived myogenic progenitor cells in humanized mice
B. Benabdallah, C. Desaulniers-Langevin, M.-L. Goyer, C. Colas, C. Maltais, Y. Li, J. V. Guimond, J. P. Tremblay, E. Haddad, C. Beausejour
This study evaluates immune tolerance of hiPSC-derived myogenic progenitor cells in humanized mice, finding autologous cells are tolerated while allogeneic grafts are rejected, and NK cell transfer prevents teratoma formation.
bioRxiv · Jul 11, 2019 · PreprintCell Biology