Author

B. Benabdallah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Beausejour· 4 shared C. Colas· 2 shared E. Haddad· 2 shared Y. Li· 2 shared A. Deprez· 1 shared A. Sonn· 1 shared C. Desaulniers-Langevin· 1 shared C. Deslauniers-Langevin· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersCell Biology

C. Beausejour

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4 papers

Recent·Most cited

Senescent human fibroblasts have increased FasL expression and impair the tumor immune response

M. Cruz, J. Dulong, G. Mansour Nehmo, A. Sonn, G. Moquin-Beaudry, B. Benabdallah, O. Le, C. Beausejour

The paper shows senescent human fibroblasts increase FasL expression, leading to T and NK cell apoptosis and impaired tumor immune response in humanized models.

bioRxiv · Jun 10, 2024 · PreprintCancer Biology

Clearance of defective muscle stem cells by senolytics reduces the expression of senescence-associated secretory phenotype and restores myogenesis in myotonic dystrophy type 1.

T. Conte, G. D. Bishop, Z. Orfi, I. Mokhtari, A. Deprez, M.-P. Roussel, I. Cote, O. Pellerito, D. Maggiorani, B. Benabdallah, S. Leclerc, L. Feulner, J. Mathieu, C. Gagnon, G. Andelfinger, , N. Dumont

This study identifies a senescent molecular signature in DM1 myogenic cells and shows that senolytics reduce SASP and restore myogenesis.

bioRxiv · Jun 22, 2022 · PreprintCell Biology

NK cells prevent the formation of teratomas derived from human induced pluripotent stem cells

B. Benabdallah, C. Deslauniers-Langevin, C. Colas, Y. Li, J. Guimond, E. Haddad, C. Beausejour

This study shows that NK cells prevent teratoma formation from hiPSCs in immune competent hosts, while autologous T cells can reject established teratomas.

bioRxiv · Jul 25, 2019Cell Biology

Immune tolerance of human induced pluripotent stem cell-derived myogenic progenitor cells in humanized mice

B. Benabdallah, C. Desaulniers-Langevin, M.-L. Goyer, C. Colas, C. Maltais, Y. Li, J. V. Guimond, J. P. Tremblay, E. Haddad, C. Beausejour

This study evaluates immune tolerance of hiPSC-derived myogenic progenitor cells in humanized mice, finding autologous cells are tolerated while allogeneic grafts are rejected, and NK cell transfer prevents teratoma formation.

bioRxiv · Jul 11, 2019 · PreprintCell Biology