EBV LMP1-activated mTORC1 and mTORC2 Coordinately Promote Nasopharyngeal Cancer Stem Cell Properties
N. Zhu, Q. Wang, Z. Wu, Y. Wang, M.-S. Zeng, Y. Yuan
This study shows that EBV LMP1 activates mTORC1 and mTORC2 to promote cancer stem cell properties in nasopharyngeal carcinoma, with distinct roles in drug resistance, tumor initiation, and metastasis.
bioRxiv · Nov 10, 2021 · PreprintCancer Biology