Author

M.R.K. Alley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Amanda R. StrohmiD· 1 shared Gauri S. ShetyeiD· 1 shared Mingqian WangiD· 1 shared Peter J. TongeiD· 1 shared Scott Gary FranzblauiD· 1 shared Siobhan A. Cohen· 1 shared Stephen G. WalkeriD· 1 shared YongLe HeiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Amanda R. StrohmORCID

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1 paper

Recent·Most cited

BiochemistryACS Chemical BiologyPeer-reviewedDec 3, 2025

Selectivity of the time-dependent M. tuberculosis LeuRS inhibitor ganfeborole is driven by target vulnerability

Mingqian Wang, YongLe He, Siobhan A. Cohen…·Peter J. Tonge

This paper shows ganfeborole is a potent time-dependent inhibitor of M. tuberculosis LeuRS with a long post-antibiotic effect, but not effective against E. coli despite inhibiting its LeuRS.

3 citations

humanmouse

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