Author

Siobhan A. Cohen

Stony Brook University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Peter J. TongeiD· 2 shared Stephen G. WalkeriD· 2 shared Alexa L. Gilberti· 1 shared Alyssa C. PollardiD· 1 shared Amanda R. StrohmiD· 1 shared Aya SabbahiD· 1 shared Eric D. BrowniD· 1 shared Franchesca Abou Said· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Peter J. TongeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Selectivity of the time-dependent M. tuberculosis LeuRS inhibitor ganfeborole is driven by target vulnerability

Mingqian Wang, YongLe He, Siobhan A. Cohen, Amanda R. Strohm, Gauri S. Shetye, Scott Gary Franzblau, Stephen G. Walker, M.R.K. Alley, Peter J. Tonge

This paper shows ganfeborole is a potent time-dependent inhibitor of M. tuberculosis LeuRS with a long post-antibiotic effect, but not effective against E. coli despite inhibiting its LeuRS.

ACS Chemical Biology · Dec 3, 2025Peer-reviewedBiochemistry

Identifying Modulators of the Post-Antibiotic Effect

Alexa L. Gilberti, Megan M. Tu, Kenneth Rachwalski, Madeeha I. Ali, Siobhan A. Cohen, Melike Akoglu, Alyssa C. Pollard, Jinnette Tolentino Collado, Aya Sabbah, Franchesca Abou Said, Purnima Dela, Stephen G. Walker, John D. Haley, Eric D. Brown, Peter J. Tonge

This paper identifies genes that enhance the post-antibiotic effect (PAE) in E. coli using a high-throughput screen of deletion strains, revealing that rfaE deletion increases PAE by stabilizing LpxC.

ACS Infectious Diseases · Aug 6, 2025Peer-reviewedMicrobiology