Coordination of genome replication and anaphase entry by rDNA copy number in S. cerevisiae
Elizabeth X. Kwan, Gina M. Alvino, Kelsey L. Lynch, Paula F. Levan, Haley M. Amemiya, Xiaobin S. Wang, Sarah Johnson, Joseph C. Sanchez, Madison A. Miller, Mackenzie Croy, Seung‐been Lee, Maria Naushab, Josh T. Cuperus, Bonita J. Brewer, Christine Queitsch, M. K. Raghuraman
The paper shows that reducing rDNA copy number in S. cerevisiae changes its replication timing, delays genome replication, and links rDNA to cell cycle control via Cdc14p sequestration.
bioRxiv · Feb 25, 2021 · PreprintMolecular Biology