Author
University of Pennsylvania
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Ling Wu, Kimberly A. Wodzanowski, Stephanie M Schreiner…·Sunny Shin
This study shows human CASP4 and CASP5 form SMOCs in response to LPS structures that evade TLR4 and Casp11, revealing their distinct roles in sensing bacterial LPS and implications for sepsis therapy.
Patrick M. Exconde, William Yoo, Madhura Kulkarni…·Cornelius Y. Taabazuing
DIPTAR converts protein degradation into a selectable phenotype to enable functional studies of degradation pathways and host-pathogen interactions.
Madhura Kulkarni, Christopher M. Bourne, Ashutosh B. Mahale…·Cornelius Y. Taabazuing
This study identifies CASP4/5 as activators of CASP3/7 and GSDME in human macrophages, showing that CASP3 restricts Salmonella replication through apoptosis.
Christopher M. Bourne, Nicole R. Raniszewski, Madhura Kulkarni…·Cornelius Y. Taabazuing
The paper develops a new peptide-based inhibitor targeting caspase-8 and reveals shared specificities between inflammatory and apoptotic caspases.