Temporal scaling of dopamine neuron firing and dopamine release by distinct ion channels shape behavior
Barbara Juarez, Mi-Seon Kong, Yong Sang Jo, Jordan E. Elum, Joshua X. Yee, Scott Ng-Evans, Marcella M. Cline, Avery C. Hunker, Meagan A. Quinlan, Madison A. Baird, Abigail J. Elerding, Mia Johnson, Derek Ban, Adriana Mendez, Nastacia L. Goodwin, , Larry S. Zweifel
This study shows that Kv4.3 and BKCa1.1 ion channels regulate dopamine neuron firing and release on different time scales, influencing distinct phases of reinforced behavior in mice.
Science Advances · Aug 11, 2023Peer-reviewedNeuroscience