Author

Michael E. Ivan

University of MiamiORCID 0000-0002-4798-4989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Macarena Ines de la FuenteiD· 2 shared Madison Sharp· 2 shared Matthew D’AntuonoiD· 2 shared Nagi G. AyadiD· 2 shared Ricardo J. KomotariD· 2 shared Rishika ChowdaryiD· 2 shared Robert K. SuteriD· 2 shared Adam M. SonabendiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Macarena Ines de la FuenteORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations

Robert K. Suter, Anna M. Jermakowicz, Rithvik Veeramachaneni, Matthew D’Antuono, L.G. Zhang, Rishika Chowdary, Simon Kaeppeli, Madison Sharp, Pravallika Palwai, Vasileios Stathias, Grace Baker, Luz Clarita Ruiz, Winston M. Walters, Maria L. Cepero, Danielle M. Burgenske, , Nagi G. Ayad

The paper integrates single-cell RNA sequencing data with drug response signatures to identify drug-sensitive and resistant glioblastoma cell states and predict synergistic drug combinations.

Nature Communications · Jan 7, 2026Peer-reviewedCancer Biology

Targeting ZNF638 activates antiviral immune responses and potentiates immune checkpoint inhibition in glioblastoma

Deepa Seetharam, Jay S. Chandar, Christian Kieran Ramsoomair, Jelisah Desgraves, Alexandra Alvarado Medina, Anna Jane Hudson, Ava Amidei, Jesús Castro, Vaidya Govindarajan, Sarah Wang, Yong Zhang, Adam M. Sonabend, Mynor J. Mendez Valdez, Dragan Maric, Vasundara Govindarajan, , Ashish Harish Shah

This study shows targeting ZNF638 induces viral mimicry and enhances immune checkpoint inhibition in glioblastoma by increasing dsRNA signaling and PD-L1 expression.

Journal of Clinical Investigation · Mar 16, 2025Peer-reviewedCancer Biology

Identification of disease-specific vulnerability states at the single-cell level

Matthew D’Antuono, Madison Sharp, Rishika Chowdary, Michael E. Ivan, Ricardo J. Komotar, Robert K. Suter, Nagi G. Ayad

The paper identifies three single-cell vulnerability states in glioblastoma using transcriptomic data and CRISPR screens, showing differential drug sensitivity and spatial distribution.

bioRxiv · Dec 4, 2024 · PreprintCancer Biology