Author

Magda E. Lotkowska

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Organism:rat· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Geetha SankaranarayananiD· 3 shared Matthew BerrimaniD· 3 shared Alan TraceyiD· 2 shared Gabriel RinaldiiD· 2 shared Nancy E. HolroydiD· 2 shared Adam WeissiD· 1 shared Albrecht I. Schulte‐HosteddeiD· 1 shared Avril CoghlaniD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersDevelopmental Biology

Geetha SankaranarayananORCID

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Author profile →

3 papers

Recent·Most cited

In vitro sexual dimorphism establishment in schistosomes

Rémi Pichon, Magda E. Lotkowska, Jude LD Bulathsinghalage, Madeleine McMath, Mary Evans, Benjamin J. Hulme, Kirsty Ambridge, Geetha Sankaranarayanan, Simon Kershenbaum, Sarah D. Davey, Josephine Forde-Thomas, Karl F. Hoffmann, Matthew Berriman, Gabriel Rinaldi

This paper refines an in vitro protocol for culturing schistosomes to achieve sexual dimorphism, showing that human serum promotes red blood cell digestion and sexual differentiation compared to fetal bovine serum.

eLife · Sep 10, 2026Peer-reviewedDevelopmental Biology

Population genomic evidence that human and animal infections in Africa come from the same populations of Dracunculus medinensis

Caroline Durrant, Elizabeth A. Thiele, Nancy E. Holroyd, Stephen R. Doyle, Guillaume Sallé, Alan Tracey, Geetha Sankaranarayanan, Magda E. Lotkowska, Hayley M. Bennett, Thomas Huckvale, Zahra Abdellah, Philip Tchindebet Ouakou, Mesfin Wossen, Makoy Samuel Yibi Logora, Cheick Oumar Coulibaly, , James Anthony Cotton

The paper uses genomic data from Guinea worm infections in humans and dogs to show they originate from the same population, indicating transmission between species and a population bottleneck.

PLoS neglected tropical diseases · Nov 30, 2020Peer-reviewedGenomics

Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni

Geetha Sankaranarayanan, Avril Coghlan, Patrick Driguez, Magda E. Lotkowska, Mandy J Sanders, Nancy E. Holroyd, Alan Tracey, Matthew Berriman, Gabriel Rinaldi

This study uses CRISPR-Cas9 to induce deletions in the SULT-OR gene of Schistosoma mansoni, showing potential for oxamniquine resistance but limited mRNA knockdown due to low mutation frequency.

Wellcome Open Research · Jul 23, 2020Peer-reviewedMolecular Biology