Maitreya J Dunham

Single-molecule sequencing and conformational capture enable de novo mammalian reference genomes

This paper presents a de novo mammalian genome assembly for the domestic goat using long-read sequencing, short-read validation, and chromatin interaction mapping, achieving high contiguity and resolving repetitive regions.

Empirical determinants of adaptive mutations in yeast experimental evolution

The paper identifies adaptive mutations in yeast experimental evolution by comparing potential beneficial mutations with those observed, finding that half of the mutations improve fitness and alternative mutations can be selected.