Author

Malik Khelfaoui

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Aude-Marie Lepagnol-BesteliD· 2 shared Jean‐Christophe RainiD· 2 shared Julia Viard· 2 shared Michel SimonneauiD· 2 shared Rachel Daudin· 2 shared Yann HéraultiD· 2 shared Yann Loe-MieiD· 2 shared Anne BolandiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Aude-Marie Lepagnol-BestelORCID

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2 papers

Recent·Most cited

AUTS2 gene dosage affects synaptic AMPA receptors via a local dendritic spine AUTS2-TTC3-AKT-mTORC1 signaling dysfunction

Aude-Marie Lepagnol-Bestel, Arnaud Duchon, Julia Viard, Mirna Kvajo, Rachel Daudin, Malik Khelfaoui, Simon Haziza, Yann Loe-Mie, Mattia Aime, Futoshi Suizu, Marie‐Christine Birling, Mounia Bensaid, Sylvie Jacquot, Pascale Koebel, Céline Reverdy, , Michel Simonneau

This study shows that AUTS2 gene dosage affects synaptic AMPA receptors through the AUTS2-TTC3-AKT-mTORC1 pathway, leading to behavioral and cognitive impairments in mice.

bioRxiv · Dec 1, 2022 · PreprintNeuroscience

Chr21 protein-protein interactions: enrichment in products involved in intellectual disabilities, autism and Late Onset Alzheimer Disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plançon, Anne Boland, Francisco J. Tejedor, Richard L. Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Y. Yu, Valérie Hindie, , Aude-Marie Lepagnol-Bestel

The paper identifies protein-protein interactions on Chr21 linked to intellectual disabilities, autism, and Alzheimer's by analyzing yeast two-hybrid screens and synaptic localization.

bioRxiv · Dec 11, 2019 · PreprintNeuroscience