Author

Margaret A. Yin

Broad Institute

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

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Ahmet S. AsaniD· 1 shared Ally A. NicolellaiD· 1 shared Ana Geller· 1 shared Bryan J. SongiD· 1 shared Chuhan GengiD· 1 shared Hasmik KeshishianiD· 1 shared Jen Q. PaniD· 1 shared Katherine J. StalnakeriD· 1 shared

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Ahmet S. AsanORCID

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Recent·Most cited

NeurosciencebioRxivPreprintOct 10, 2024

SRRM2 haploinsufficiency drives SynGAP-γ reduction, Agap3 mis-splicing, and oligodendrocyte deficits in a mouse model of schizophrenia

Sameer Aryal, Chuhan Geng, Margaret A. Yin…·Morgan Sheng

This study shows that SRRM2 haploinsufficiency in mice causes synaptic, splicing, and myelination defects linked to schizophrenia-like behaviors and gene expression changes.

5 citations

mousebulk RNA-seq

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