Author

Maria Nigos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Efthymia PapalexiiD· 3 shared Ryan T. KoehleriD· 3 shared Sarah Schroeder· 3 shared Vuong TraniD· 3 shared Ajay Sapre· 2 shared Alexander Rosenberg· 2 shared Bryan HariadiiD· 2 shared Charles Roco· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Efthymia PapalexiORCID

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Author profile →

3 papers

Recent·Most cited

A single-cell cytokine dictionary of human peripheral blood

Fabian Joachim Theis, Lukas Oesinghaus, Sören Becker, Larsen Vornholz, Efthymia Papalexi, Joey Pangallo, Amir Moinfar, Jenni Liu, Alyssa La Fleur, Maiia Shulman, Simone Marrujo, Bryan Hariadi, Crina Curca, Alexa Suyama, Maria Nigos, , Georg Seelig

The paper creates a Human Cytokine Dictionary using single-cell transcriptomes of PBMCs stimulated with cytokines, revealing cell-type-specific responses and communication networks.

bioRxiv · Dec 15, 2025 · PreprintImmunology

Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling

Jesse M. Zhang, Airol A. Ubas, Richard de Borja, Valentine Svensson, Nicole Thomas, Neha Thakar, Ian K. Lai, Aidan F. Winters, Umair Khan, Matthew G. Jones, John D. Thompson, Vuong Tran, Joseph Pangallo, Efthymia Papalexi, Ajay Sapre, , Johnny X. Yu

A 100-million-cell atlas: 50 cancer lines pooled as spheroid villages, treated with 379 drugs at several doses, profiled by combinatorial-barcoding scRNA-seq and embedded with a 10-dimensional scVI model.

bioRxiv · Feb 20, 2025 · PreprintGenomics✦ In-depth digest

High sensitivity single cell RNA sequencing with split pool barcoding

Vuong Tran, Efthymia Papalexi, Sarah Schroeder, Grace S. Kim, Ajay A. Sapre, Joey Pangallo, Alex Sova, Peter Matulich, Lauren Kenyon, Zeynep Sayar, Ryan T. Koehler, Daniel Diaz, Archita Gadkari, Kamy J. Howitz, Maria Nigos, , Alexander B. Rosenberg

This paper introduces an improved combinatorial barcoding method for scRNA-seq that significantly increases sensitivity, detecting more transcripts and genes per cell across various sample types.

bioRxiv · Aug 27, 2022 · PreprintGenomics