Single cell view of tumor microenvironment gradients in pleural mesothelioma
Bruno Giotti, Komal Dolasia, William Zhao, Peiwen Cai, Robert Sweeney, Elliot Merritt, Evgeny Kiner, Grace S. Kim, Atharva Bhagwat, Thinh Nguyen, Samarth Hegde, Bailey G. Fitzgerald, Sanjana Shroff, Travis Dawson, Monica Garcia-Barros, , Alexander M. Tsankov
This paper uses single-cell RNA-sequencing to analyze the tumor microenvironment in pleural mesothelioma, identifying gene programs, fetal-like endothelial cells, and a new therapeutic target.
bioRxiv · Mar 14, 2024Cancer Biology