Distinct roles for MNK1 and MNK2 in social and cognitive behavior through kinase-specific regulation of the synaptic proteome and phosphoproteome
Rosalba Olga Proce, Maria Steinecker, Chiara Giacomelli, Erika Uddstrom, Anirban Chatterjee, Souhaila Wusthoff, Luiz Gustavo Teixeira Alves, Oliver Popp, Tobias T. Pohl, Katie Maxwell, Lucie Hortmann, Séverine Kunz, Philipp Mertins, Markus Landthaler, Daria Bunina, Hanna Hörnberg
This study shows that MNK1 and MNK2 have distinct roles in social and cognitive behaviors by regulating different aspects of the synaptic proteome and phosphoproteome in knockout mice.
Molecular Psychiatry · Feb 13, 2026Peer-reviewedNeuroscience