Martin Lehmann

This study shows that endogenous PEX14 localizes to mitochondria and is essential for peroxisome biogenesis.

The paper determines the molecular structures of SYTOX Orange and SYTOX Green, characterizes their effects on DNA mechanics using magnetic tweezers, and reports their photophysical properties.

This study reveals how CPP-additives enable direct membrane translocation of proteins by inducing transient water pores, offering insights for optimizing protein delivery strategies.

This study identifies septin-associated PIPKIγ splice variants as essential for midbody organization by generating PI(4,5)P2 required for centralspindlin recruitment and septin-microtubule association.

The paper introduces a one-step method to create cell-impermeable fluorescent HaloTag substrates for live-cell imaging and super-resolution microscopy.

This paper structurally characterizes CCDC127 as a mitochondrial intermembrane space protein involved in the mitoskeleton framework.

This study shows that dietary lipids induce caveolae uptake, caveolin1 accumulation to lipid droplets, and caveolin1-dependent lipid droplet growth.

This paper introduces a knock-in mouse line with endogenous Munc13-1-SNAP for monitoring presynaptic nanoarchitecture using SNAP-tag labeling and live-cell imaging.

The paper presents a morphological profiling dataset of EU-OPENSCREEN bioactive compounds across multiple imaging sites and cell lines, validated for robustness and used to map profiles to activity and toxicity.

This paper develops a fluorescent probe to detect malaria-infected red blood cells and demonstrates its use with a smartphone microscope for diagnostic applications.

The paper uses integrative molecular dynamics simulations to analyze cross-linking mass spectrometry data and reveal mitochondrial protein distributions, including the localization of FAM162A and TMEM126A in cristae.

This paper introduces CLASP, a cross-link assisted spatial proteomics method, to map sub-organelle proteomes and membrane protein topology in human mitochondria.

The paper identifies RAB2's role in presynaptic precursor vesicle biogenesis at the trans-Golgi network, showing its necessity for proper protein transport and neurotransmission.

The paper identifies Pttg1 and Ulk4 as genetic modifiers that enhance SHH pathway resilience and are involved in primary cilia formation in the neuroepithelium.

This study shows RIM-BP2 has different roles in neurotransmitter release at hippocampal mossy fiber and pyramidal CA3-CA1 synapses, with RIM-BP2 promoting vesicle docking/priming at mossy fibers by recruiting Munc13-1.

The paper identifies a molecular mechanism for presynaptic plasticity involving rapid remodeling of active zone modules, which sustains neurotransmitter release potentiation over time.